Rebello, Sam S.: search on Z-Library

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1

Simultaneous physiologically-based pharmacokinetic (PBPK) modeling of parent and active metabolites to investigate complex CYP3A4 drug-drug interaction potential: a case example of midostaurin

Gu, Helen, Dutreix, Catherine, Rebello, Sam, Ouatas, Taoufik, Wang, Lai, Chun, Dung Yu, Einolf, Heidi J, He, Handan

Journal:

Drug Metabolism and Disposition

Year:

2017

Language:

english

File:

PDF, 6.29 MB

english, 2017

2

Assessment of pharmacokinetic drug-drug interaction between pradigastat and acetaminophen in healthy subjects

Ayalasomayajula, Surya, Meyers, Dan, Koo, Phillip, Salunke, Atish, Majumdar, Tapan, Rebello, Sam, Sunkara, Gangadhar, Chen, Jin

Journal:

European Journal of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 412 KB

english, 2015

3

Contribution of in vivo models of thrombosis to the discovery and development of novel antithrombotic agents

Robert J. Leadley Jr., Liguo Chi, Sam S. Rebello, Alison Gagnon

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2000

Language:

english

File:

PDF, 256 KB

english, 2000

4

Ontogeny of endothelin and its receptors in rat brain

Anil Gulati, Sam Rebello, Gopal Chari, Rama Bhat

Journal:

Year:

1992

Language:

english

File:

PDF, 544 KB

english, 1992

5

Systemic hemodynamic and regional circulatory effects of centrally administered endothelin-1 are mediated through ETA receptors

Sam Rebello, Sujoy Roy, Pramod R. Saxena, Anil Gulati

Journal:

Year:

1995

Language:

english

File:

PDF, 1.05 MB

english, 1995

6

Correlation between the in vivoEff icacy of GPIIb/IIIa Receptor Antagonists (m7E3, MK-383 and DMP-728) and ex vivo Platelet Inhibition

Huang, Jinbao, Rebello, Sam S., Faul, Jessica D., Lucchesi, Benedict R.

Journal:

Year:

1999

Language:

english

File:

PDF, 353 KB

english, 1999

7

Cardiovascular Effects of Centrally Administered Endothelin-1 in Rats

Gulati, Anil, Rebello, Sam, Roy, Sujoy, Saxena, Pramod R.

Journal:

Journal of Cardiovascular Pharmacology

Year:

1995

File:

PDF, 198 KB

1995

8

Assessment of pharmacokinetic drug-drug interaction between pradigastat and atazanavir or probenecid

Mendonza, Anisha, Hanna, Imad, Meyers, Dan, Koo, Phillip, Neelakantham, Srikanth, Zhu, Bing, Majumdar, Tapan, Rebello, Sam, Sunkara, Gangadhar, Chen, Jin

Journal:

Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 312 KB

english, 2016

9

Effect of Cyclosporine on the Pharmacokinetics of Aliskiren in Healthy Subjects

Rebello, Sam, Compain, Séverine, Feng, Aimin, Hariry, Sam, Dieterich, Hans-Armin, Jarugula, Venkateswar

Journal:

Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 242 KB

english, 2011

10

Evaluation of food effect on the oral bioavailability of pradigastat, a diacylglycerol acyltransferase 1 inhibitor

Ayalasomayajula, Surya P., Meyers, Charles D., Yu, Jing, Kagan, Mark, Matott, Ralph, Pal, Parasar, Majumdar, Tapan, Su, Zhenzhong, Crissey, Anne, Rebello, Sam, Sunkara, Gangadhar, Chen, Jin

Journal:

Biopharmaceutics & Drug Disposition

Year:

2015

Language:

english

File:

PDF, 304 KB

english, 2015

11

Endothelin mechanisms in altered thyroid states in the rat

Sam Rebello, Emmanuel B. Thompson, Anil Gulati

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 758 KB

english, 1993

12

Pharmacokinetic and pharmacodynamic drug-drug interaction assessment between pradigastat and digoxin or warfarin

Yan, Jing-He, Meyers, Dan, Lee, Zachary, Danis, Kate, Neelakantham, Srikanth, Majumdar, Tapan, Rebello, Sam, Sunkara, Gangadhar, Chen, Jin

Journal:

Journal of Clinical Pharmacology

Year:

2014

Language:

english

File:

PDF, 443 KB

english, 2014

13

Effect of Verapamil on the Pharmacokinetics of Aliskiren in Healthy Participants

Rebello, Sam, Leon, Selene, Hariry, Sam, Dahlke, Marion, Jarugula, Venkateswar

Journal:

Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 304 KB

english, 2011

14

Role of Short-Term Inhibition of Factor Xa by FXV673 in Arterial Passivation: A Study in a Chronic Model of Thrombosis in Conscious Dogs

Rebello, Sam S., Kasiewski, Charles J., Wang, Wei, Bentley, Ross G., Morgan, Suzanne R., Chu, Valeria, Colussi, Dennis, Brown, Karen, Perrone, Mark H., Leadley, Robert J.

Journal:

Journal of Cardiovascular Pharmacology

Year:

2001

Language:

english

File:

PDF, 3.39 MB

english, 2001

15

Regional Circulatory and Systemic Hemodynamic Effects of Diaspirin Cross-Linked Hemoglobin in the Rat

Sharma, Avadhesh C., Rebello, Sam, Gulati, Anil

Journal:

Artificial Cells Blood Substitutes and Biotechnology

Year:

1994

Language:

english

File:

PDF, 645 KB

english, 1994

16

AIP Conference Proceedings [AIP 2010 PHYSICS EDUCATION RESEARCH CONFERENCE - Portland, (Oregon) (21–22 July 2010)] - TA Beliefs in a SCALE-UP Style Classroom

DeBeck, George, Settelmeyer, Sam, Li, Sissi, Demaree, Dedra, Singh, Chandralekha, Sabella, Mel, Rebello, Sanjay

Year:

2010

Language:

english

File:

PDF, 77 KB

english, 2010

17

Correlation between the in vivoEff icacy of GPIIb/IIIa Receptor Antagonists (m7E3, MK-383 and DMP-728) and ex vivo Platelet Inhibition

Huang, Jinbao, Rebello, Sam S., Faul, Jessica D., Lucchesi, Benedict R.

Journal:

Year:

1999

File:

PDF, 353 KB

1999

18

Effect of Renal Impairment on the Pharmacokinetics of Pradigastat, a Novel Diacylglycerol Acyltransferase1 (DGAT1) Inhibitor

Mita, Sachiko, Meyers, Dan, Pal, Parasar, Lin, TsuHan, Majumdar, Tapan, Rebello, Sam, Sunkara, Gangadhar, Chen, Jin

Journal:

Clinical Pharmacokinetics

Year:

2015

Language:

english

File:

PDF, 437 KB

english, 2015

19

Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects

Sam Rebello, Sally Zhao, Sam Hariry, Marion Dahlke, Natalya Alexander, Arpine Vapurcuyan, Imad Hanna, Venkateswar Jarugula

Journal:

European Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 396 KB

english, 2012

20

Antithrombotic Efficacy of Single Subcutaneous Administration of a Recombinant Nematode Anticoagulant Peptide (rNAP5) in a Canine Model of Coronary Artery Thrombolysis

Sam S Rebello, Howard S Blank, Benedict R Lucchesi

Journal:

Thrombosis Research

Year:

2000

Language:

english

File:

PDF, 193 KB

english, 2000

21

HORMONAL AND ELECTROLYTE RESPONSES TO THE ALDOSTERONE SYNTHASE INHIBITOR LCI699 IN SODIUM DEPLETED HEALTHY SUBJECTS

Joël Menard, Catherine Watson, Sam Rebello, Yiming M. Zhang, William P. Dole

Journal:

Journal of the American College of Cardiology

Year:

2010

Language:

english

File:

PDF, 61 KB

english, 2010

22

Characteristics of endothelin receptors in the cerebral cortex and spinal cord of aged rats

Bertelsen, Greg A., Rebello, Sam, Gulati, Anil

Journal:

Neurobiology of Aging

Year:

1992

Language:

english

File:

PDF, 640 KB

english, 1992

23

Compelling Relationship of CYP3A Induction to Levels of the Putative Biomarker 4β-Hydroxycholesterol and Changes in Midazolam Exposure

Mangold, James B., Wu, Fan, Rebello, Sam

Journal:

Clinical Pharmacology in Drug Development

Year:

2016

Language:

english

File:

PDF, 142 KB

english, 2016

24

Safety, Tolerability, and Physiological Effects of AXA1665, a Novel Composition of Amino Acids, in Subjects With ChildâPugh A and B Cirrhosis

Chakravarthy, Manu V., Neutel, Joel, Confer, Scharmen, Zhao, Peng, Tatsuta, Noriaki, Rebello, Sam, Comb, William C., Hamill, Michael, Tramontin, Tony, Carroll, Sean, Afeyan, Raffi, Sanyal, Arun J.

Journal:

Clinical and Translational Gastroenterology

Year:

2020

File:

PDF, 1.58 MB

2020

25

Structure-based library design and the discovery of a potent and selective mast cell β-tryptase inhibitor as an oral therapeutic agent

Guyan Liang, Suzanne Aldous, Gregory Merriman, Julian Levell, James Pribish, Jennifer Cairns, Xin Chen, Sebastien Maignan, Magali Mathieu, Joseph Tsay, Keith Sides, Sam Rebello, Brian Whitely, Isabell

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 943 KB

english, 2012

26

Effect of diaspirin crosslinked and stroma-reduced hemoglobin on mean arterial pressure and endothelin-1 concentration in rats

Anil Gulati, Govind Singh, Sam Rebello, Avadhesh C. Sharma

Journal:

Year:

1995

Language:

english

File:

PDF, 775 KB

english, 1995

27

Effect of time of 7E3 administration on rt-PA-induced reperfusion: study in a canine model of thrombus-based occlusion–reperfusion

Sam S Rebello, Jinbao Huang, Kumi Saito, Jorge F Saucedo, Eric R Bates, Benedict R Lucchesi

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 474 KB

english, 1999

28

Pharmacokinetics of Aliskiren in Patients with End-Stage Renal Disease Undergoing Haemodialysis

Dmytro Khadzhynov, Torsten Slowinski, Ina Lieker, Hans-Hellmut Neumayer, Diego Albrecht, Henk Johan Streefkerk, Sam Rebello, Harm Peters

Journal:

Clinical Pharmacokinetics

Year:

2012

Language:

english

File:

PDF, 435 KB

english, 2012

29

Pharmacokinetic drug-drug interaction assessment between LCZ696, an angiotensin receptor neprilysin inhibitor, and hydrochlorothiazide, amlodipine, or carvedilol

Hsiao, Hsiu-ling, Langenickel, Thomas Heiko, Greeley, Michael, Roberts, John, Zhou, Wei, Pal, Parasar, Rebello, Sam, Rajman, Iris, Sunkara, Gangadhar

Journal:

Clinical Pharmacology in Drug Development

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

30

Disposition of morphine in plasma and cerebrospinal fluid varies during neonatal development in pigs

Aarati Rai, Shaifali Bhalla, Sam S. Rebello, Helen Kastrissios, Anil Gulati

Journal:

Journal of Pharmacy and Pharmacology

Year:

2005

Language:

english

File:

PDF, 118 KB

english, 2005

31

Design, synthesis, and biological activity of potent and selective inhibitors of mast cell tryptase

Corey R. Hopkins, Mark Czekaj, Steven S. Kaye, Zhongli Gao, James Pribish, Henry Pauls, Guyan Liang, Keith Sides, Dona Cramer, Jennifer Cairns, Yongyi Luo, Heng-Keang Lim, Roy Vaz, Sam Rebello, Sebast

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 310 KB

english, 2005

32

Antithrombotic efficacy of a novel factor Xa inhibitor, FXV673, in a canine model of coronary artery thrombolysis

Sam S Rebello, Ross G Bentley, Suzanne R Morgan, Charles J Kasiewski, Valeria Chu, Mark H Perrone, Robert J Leadley

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 181 KB

english, 2001

33

Thrombostatin Inhibits Induced Canine Coronary Thrombosis

Hasan, Ahmed, Rebello, Sam, Smith, Edward, Srikanth, Sujata, Werns, Steven, Driscoll, Edward, Faul, Jessica, Brenner, Dean, Normolle, Daniel, Lucchesi, Benedict, Schmaier, Alvin

Journal:

Thrombosis and Haemostasis

Year:

1999

Language:

english

File:

PDF, 92 KB

english, 1999

34

Temporary and partial inhibition of platelets by SM-20302 prevents coronary artery thrombosis in a chronic canine model

Jinbao Huang, Sam S. Rebello, Lewis A. Rosenberg, Munekiyo Kaneko, Teruo Sakurama, Benedict R. Lucchesi

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 222 KB

english, 1999

35

Effects of age and sex on the pharmacokinetics of LCZ696, an angiotensin receptor neprilysin inhibitor

Gan, Lu, Langenickel, Thomas, Petruck, Jesika, Kode, Kiran, Rajman, Iris, Chandra, Priya, Zhou, Wei, Rebello, Sam, Sunkara, Gangadhar

Journal:

Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 262 KB

english, 2016

36

Superiority of Enoxaparin Over Heparin in Combination With a GPIIb/IIIa Receptor Antagonist During Coronary Thrombolysis in Dogs

Sam S Rebello, Charles J Kasiewski, Ross G Bentley, Suzanne R Morgan, Valeria Chu, Jeffrey S Bostwick, Scott I Klein, Mark H Perrone, Robert J Leadley

Journal:

Thrombosis Research

Year:

2001

Language:

english

File:

PDF, 202 KB

english, 2001

37

Down-regulation of endothelin receptors in the ventrolateral medulla of spontaneously hypertensive rats

Anil Gulati, Sam Rebello

Journal:

Year:

1991

Language:

english

File:

PDF, 625 KB

english, 1991

38

A semi-automated LC–MS/MS method for the determination of LCI699, a steroid 11β-hydroxylase inhibitor, in human plasma

Li, Wenkui, Luo, Suyi, Rebello, Sam, Flarakos, Jimmy, Tse, Francis L.S.

Journal:

Journal of Chromatography B

Year:

2014

Language:

english

File:

PDF, 2.38 MB

english, 2014

39

Diaspirin Cross-Linked Hemoglobin (DCLHB TM): Involvement of Adrenergic Mechanisms in the Pressor Effect

Gulati, Anil, Rebello, Sam

Journal:

Artificial Cells Blood Substitutes and Biotechnology

Year:

1994

Language:

english

File:

PDF, 577 KB

english, 1994

40

A Physiologically-Based Pharmacokinetic Modeling Approach To Predict Drug–Drug Interactions of Sonidegib (LDE225) with Perpetrators of CYP3A in Cancer Patients

Einolf, Heidi J., Zhou, Jocelyn, Won, Christina, Wang, Lai, Rebello, Sam

Journal:

Drug Metabolism and Disposition

Year:

2017

Language:

english

File:

PDF, 586 KB

english, 2017

41

Role of Extracellular Ionized Calcium in the In Vitro Assessment of GPIIb/IIIa Receptor Antagonists

Sam S. Rebello, Jinbao Huang, Jessica D. Faul, Benedict R. Lucchesi

Journal:

Journal of Thrombosis and Thrombolysis

Year:

2000

Language:

english

File:

PDF, 123 KB

english, 2000

42

Aldosterone synthase inhibition: cardiorenal protection in animal disease models and translation of hormonal effects to human subjects

Ménard, Joël, Rigel, Dean F, Watson, Catherine, Jeng, Arco Y, Fu, Fumin, Beil, Michael, Liu, Jing, Chen, Wei, Hu, Chii-Whei, Leung-Chu, Jennifer, LaSala, Daniel, Liang, Guiqing, Rebello, Sam, Zhang, Y

Journal:

Journal of Translational Medicine

Year:

2014

Language:

english

File:

PDF, 1.04 MB

english, 2014

43

Effect of Hepatic Impairment on the Pharmacokinetics of Pradigastat, a Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor

Hirano, Masaru, Meyers, Dan, Golla, GangaRaju, Pal, Parasar, Pinot, Pascale, Lin, TsuHan, Majumdar, Tapan, Rebello, Sam, Sunkara, Gangadhar, Chen, Jin

Journal:

Clinical Pharmacokinetics

Year:

2015

Language:

english

File:

PDF, 470 KB

english, 2015

44

An Exposure-Response Modeling Approach to Examine The Relationship Between Potency of CYP3A Inducer and Plasma 4β-Hydroxycholesterol in Healthy Subjects

Jiang, Xuemin, Dutreix, Catherine, Jarugula, Venkateswar, Rebello, Sam, Won, Christina S., Sun, Haiying

Journal:

Clinical Pharmacology in Drug Development

Year:

2016

Language:

english

File:

PDF, 493 KB

english, 2016

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